Grey’s Anatomy Season 2 started in September 2005 until May 15 and 16, 2006.   It had a three-hour season finale spanning on both nights.  This season takes a lot longer than the first - with 27 episodes, 5 of which were carried over from season 1. 

The focus of season 2 is on Meredith’s relationship with Dr. Derek Shepherd which stopped when Dr. Shepherd married Dr. Addison Montgomery.  Izzie Stevens also had a relationship with Alex Karev which did not last long because Izzie fell in love with heart patient, Denny Duquette.

Also in this season, Dr. Miranda Bailey becomes pregnant and more about Meredith’s tragedy is revealed.   Season 2 also ranked number 5 in the Nielsen Ranking with 19.9 million viewers.